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These behaviors can be caused by an on-access virus scanner trying to scan the file while the .NET framework attempts to compile the ASP.NET file.
Disable on-access scanning for the temporary ASP.NET directory and all sub-folders. The folder specifically used by ASP.NET for MailMarshal SPE is:
%WINDIR%\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files
If you run multiple versions of the .net framework, you should exclude the entire framework directory
%WINDIR%\Microsoft.NET\
On access scanning must also exclude any MailMarshal SMTP directories if on the same machine. For more information, see Trustwave Knowledgebase article Q10850.
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